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1

From Diabetes Care to Diabetes Cure—The Integration of Systems Biology, eHealth, and Behavioral Change

van Ommen, Ben, Wopereis, Suzan, van Empelen, Pepijn, van Keulen, Hilde M., Otten, Wilma, Kasteleyn, Marise, Molema, Johanna J. W., de Hoogh, Iris M., Chavannes, Niels H., Numans, Mattijs E., Evers, A

Journal:

Frontiers in Endocrinology

Year:

2018

Language:

english

File:

PDF, 1.75 MB

english, 2018

2

Nutrigenomics: exploiting systems biology in the nutrition and health arena

Ben van Ommen, Rob Stierum

Journal:

Current Opinion in Biotechnology

Year:

2002

Language:

english

File:

PDF, 54 KB

english, 2002

3

The challenges for molecular nutrition research 3: comparative nutrigenomics research as a basis for entering the systems level

Hannelore Daniel, Christian A. Drevon, Ulla I. Klein, Robert Kleemann, Ben van Ommen

Journal:

Genes & Nutrition

Year:

2008

Language:

english

File:

PDF, 208 KB

english, 2008

4

Toxicogenomic analysis of gene expression changes in rat liver after a 28-day oral benzene exposure

Wilbert H.M. Heijne, Diana Jonker, Rob H. Stierum, Ben van Ommen, John P. Groten

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2005

Language:

english

File:

PDF, 345 KB

english, 2005

5

Large-Scale Human Metabolomics Studies: A Strategy for Data (Pre-) Processing and Validation

Bijlsma, Sabina, Bobeldijk, Ivana, Verheij, Elwin R., Ramaker, Raymond, Kochhar, Sunil, Macdonald, Ian A., van Ommen, Ben, Smilde, Age K.

Journal:

Analytical Chemistry

Year:

2006

Language:

english

File:

PDF, 145 KB

english, 2006

6

S17081 - Environmental Forces that Shape Early Development: What we know and still need to know.

Shankar, Kartik, Pivik, R. T, Johnson, Susan L., van Ommen, Ben, Demmer, Elieke, Murray, Robert

Journal:

Current Developments in Nutrition

Year:

2017

Language:

english

File:

PDF, 397 KB

english, 2017

7

Detecting regime transitions in slurry bubble columns using pressure time series

Keshav C. Ruthiya, Vinit P. Chilekar, Maurice J. F. Warnier, John van der Schaaf, Ben F. M. Kuster, Jaap C. Schouten, J. Ruud van Ommen

Journal:

Year:

2005

Language:

english

File:

PDF, 466 KB

english, 2005

8

Challenging homeostasis to define biomarkers for nutrition related health

Ben van Ommen, Jaap Keijer, Sandra G. Heil, Jim Kaput

Journal:

Molecular Nutrition & Food Research

Year:

2009

Language:

english

File:

PDF, 1.39 MB

english, 2009

9

Chemical and enzyme-catalysed synthesis of quinoline arene hydrates

Rajiv Agarwal, Derek R. Boyd, Narain D. Sharma, R. Austin, S. McMordie, H.Patricia Porter, Ben van Ommen, Peter J. van Bladeren

Journal:

Bioorganic & Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 1006 KB

english, 1994

10

Discovery of subtle effects in a human intervention trial through multilevel modeling

Carina M. Rubingh, Marjan J. van Erk, Suzan Wopereis, Trinette van Vliet, Elwin R. Verheij, Nicole H.P. Cnubben, Ben van Ommen, Jan van der Greef, Henk F.J. Hendriks, Age K. Smilde

Journal:

Chemometrics and Intelligent Laboratory Systems

Year:

2011

Language:

english

File:

PDF, 816 KB

english, 2011

11

An improved method for the separation and quantification of glutathione S-transferase subunits in rat tissue using high-performance liquid chromatography

Jan J.P. Bogaards, Ben van Ommen, Peter J. van Bladeren

Journal:

Journal of Chromatography A

Year:

1989

Language:

english

File:

PDF, 366 KB

english, 1989

12

Proteome analysis reveals novel proteins associated with proliferation and differentiation of the colorectal cancer cell line Caco-2

Rob Stierum, Marco Gaspari, Yvonne Dommels, Taoufik Ouatas, Helma Pluk, Sonja Jespersen, Jack Vogels, Kitty Verhoeckx, John Groten, Ben van Ommen

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2003

Language:

english

File:

PDF, 1.44 MB

english, 2003

13

A Systems Biology Strategy for Predicting Similarities and Differences of Drug Effects: Evidence for Drug-specific Modulation of Inflammation in Atherosclerosis

Robert Kleemann, Svetlana Bureeva, Ally Perlina, Jim Kaput, Lars Verschuren, Peter Y Wielinga, Eva Hurt-Camejo, Yuri Nikolsky, Ben van Ommen, Teake Kooistra

Journal:

BMC Systems Biology

Year:

2011

Language:

english

File:

PDF, 1.62 MB

english, 2011

14

Visualization and identification of health space, based on personalized molecular phenotype and treatment response to relevant underlying biological processes

Jildau Bouwman, Jack TWE Vogels, Suzan Wopereis, Carina M Rubingh, Sabina Bijlsma, Ben van Ommen

Journal:

BMC Medical Genomics

Year:

2012

Language:

english

File:

PDF, 622 KB

english, 2012

15

Harnessing Nutrigenomics: Development of web-based communication, databases, resources, and tools

Jim Kaput, Siân Astley, Marten Renkema, Jose Ordovas, Ben van Ommen

Journal:

Genes & Nutrition

Year:

2006

Language:

english

File:

PDF, 422 KB

english, 2006

16

Mass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research

Augustin Scalbert, Lorraine Brennan, Oliver Fiehn, Thomas Hankemeier, Bruce S. Kristal, Ben van Ommen, Estelle Pujos-Guillot, Elwin Verheij, David Wishart, Suzan Wopereis

Journal:

Year:

2009

Language:

english

File:

PDF, 403 KB

english, 2009

17

Personalized nutrition from a health perspective: luxury or necessity?

Journal:

Genes & Nutrition

Year:

2007

Language:

english

File:

PDF, 81 KB

english, 2007

18

The challenges for molecular nutrition research 2: quantification of the nutritional phenotype

Ben van Ommen, Jaap Keijer, Robert Kleemann, Ruan Elliott, Christian A. Drevon, Harry McArdle, Mike Gibney, Michael Müller

Journal:

Genes & Nutrition

Year:

2008

Language:

english

File:

PDF, 297 KB

english, 2008

19

The challenges for molecular nutrition research 4: the “nutritional systems biology level”

Ben van Ommen, Duccio Cavallieri, Helen M. Roche, Ulla I. Klein, Hannelore Daniel

Journal:

Genes & Nutrition

Year:

2008

Language:

english

File:

PDF, 265 KB

english, 2008

20

The challenges for molecular nutrition research 1: linking genotype to healthy nutrition

Christine M. Williams, Jose M. Ordovas, Dennis Lairon, John Hesketh, Georg Lietz, Mike Gibney, Ben van Ommen

Journal:

Genes & Nutrition

Year:

2008

Language:

english

File:

PDF, 267 KB

english, 2008

21

Short-term fatty acid intervention elicits differential gene expression responses in adipose tissue from lean and overweight men

Marjan J. van Erk, Wilrike J. Pasman, Heleen M. Wortelboer, Ben van Ommen, Henk F. J. Hendriks

Journal:

Genes & Nutrition

Year:

2008

Language:

english

File:

PDF, 532 KB

english, 2008

22

Effect of body fat distribution on the transcription response to dietary fat interventions

Marijana Radonjic, Marjan J. van Erk, Wilrike J. Pasman, Heleen M. Wortelboer, Henk F. J. Hendriks, Ben van Ommen

Journal:

Genes & Nutrition

Year:

2009

Language:

english

File:

PDF, 378 KB

english, 2009

23

Challenges of molecular nutrition research 6: the nutritional phenotype database to store, share and evaluate nutritional systems biology studies

Ben van Ommen, Jildau Bouwman, Lars O. Dragsted, Christian A. Drevon, Ruan Elliott, Philip de Groot, Jim Kaput, John C. Mathers, Michael Müller, Fre Pepping, Jahn Saito, Augustin Scalbert, Marijana Ra

Journal:

Genes & Nutrition

Year:

2010

Language:

english

File:

PDF, 487 KB

english, 2010

24

The Micronutrient Genomics Project: a community-driven knowledge base for micronutrient research

Ben van Ommen, Ahmed El-Sohemy, John Hesketh, Jim Kaput, Michael Fenech, Chris T. Evelo, Harry J. McArdle, Jildau Bouwman, Georg Lietz, John C. Mathers, Sue Fairweather-Tait, Henk van Kranen, Ruan Ell

Journal:

Genes & Nutrition

Year:

2010

Language:

english

File:

PDF, 506 KB

english, 2010

25

Connecting the Human Variome Project to nutrigenomics

Jim Kaput, Chris T. Evelo, Giuditta Perozzi, Ben van Ommen, Richard Cotton

Journal:

Genes & Nutrition

Year:

2010

Language:

english

File:

PDF, 331 KB

english, 2010

26

Plasma metabolomics and proteomics profiling after a postprandial challenge reveal subtle diet effects on human metabolic status

Linette Pellis, Marjan J. van Erk, Ben van Ommen, Gertruud C. M. Bakker, Henk F. J. Hendriks, Nicole H. P. Cnubben, Robert Kleemann, Eugene P. van Someren, Ivana Bobeldijk, Carina M. Rubingh, Suzan Wo

Journal:

Year:

2012

Language:

english

File:

PDF, 517 KB

english, 2012

27

The microsomal metabolism of pentachlorophenol and its covalent binding to protein and DNA

Ben van Ommen, Anton Adang, Franz Müller, Peter J. van Bladeren

Journal:

Chemico-Biological Interactions

Year:

1986

Language:

english

File:

PDF, 595 KB

english, 1986

28

The oxidation of tetrachloro-1,4-hydroquinone by microsomes and purified cytochrome P-450b. Implications for covalent binding to protein and involvement of reactive oxygen species

Ben van Ommen, Jan Willem Voncken, Franz Müller, Peter J. van Bladeren

Journal:

Chemico-Biological Interactions

Year:

1988

Language:

english

File:

PDF, 736 KB

english, 1988

29

Irreversible inhibition of rat hepatic glutathione S-transferase isoenzymes by a series of structurally related quinones

Ria M.E. Vos, Ben Van Ommen, Mark S.J. Hoekstein, Jolanda H.M. De Goede, Peter J. Van Bladeren

Journal:

Chemico-Biological Interactions

Year:

1989

Language:

english

File:

PDF, 637 KB

english, 1989

30

Inhibition of human glutathione S-transferases by dopamine, α-methyldopa and their 5-S-glutathionyl conjugates

Jan H.T.M. Ploemen, Ben Van Ommen, Annemarie De Haan, Joke C. Venekamp, Peter J. Van Bladeren

Journal:

Chemico-Biological Interactions

Year:

1994

Language:

english

File:

PDF, 797 KB

english, 1994

31

Cytochrome P450 catalyzed metabolism of 1,2-dibromoethane in liver microsomes of differentially induced rats

Lars W. Wormhoudt, Jan H.T.M. Ploemen, Jan N.M. Commandeur, Ben van^Ommen, Peter J. van Bladeren, Nico P.E. Vermeulen

Journal:

Chemico-Biological Interactions

Year:

1996

Language:

english

File:

PDF, 903 KB

english, 1996

32

The relation between the oxidative biotransformation of hexachlorobenzene and its porphyrinogenic activity

Ben van Ommen, Willem Hendriks, Jos G.M. Bessems, Geert Geesink, Franz Müller, Peter J. van Bladeren

Journal:

Toxicology and Applied Pharmacology

Year:

1989

Language:

english

File:

PDF, 1.04 MB

english, 1989

33

Nutrigenomics:: exploiting systems biology in the nutrition and health arenas

Journal:

Year:

2004

Language:

english

File:

PDF, 307 KB

english, 2004

34

26th Hohenheim Consensus Conference, September 11, 2010 Scientific substantiation of health claims: Evidence-based nutrition

Hans Konrad Biesalski, Peter J. Aggett, Robert Anton, Paul S. Bernstein, Jeffrey Blumberg, Robert P. Heaney, Jeya Henry, John M. Nolan, David P. Richardson, Ben van Ommen, Renger F. Witkamp, Ger T. Ri

Journal:

Year:

2011

Language:

english

File:

PDF, 1.19 MB

english, 2011

35

Toxicogenomics concepts and applications to study hepatic effects of food additives and chemicals

Rob Stierum, Wilbert Heijne, Anne Kienhuis, Ben van Ommen, John Groten

Journal:

Toxicology and Applied Pharmacology

Year:

2005

Language:

english

File:

PDF, 1.46 MB

english, 2005

36

Toxicogenomics of bromobenzene hepatotoxicity: a combined transcriptomics and proteomics approach

Wilbert H.M Heijne, Rob H Stierum, Monique Slijper, Peter J van Bladeren, Ben van Ommen

Journal:

Biochemical Pharmacology

Year:

2003

Language:

english

File:

PDF, 561 KB

english, 2003

37

Antimutagenic activity of green tea and black tea extracts studied in a dynamic in vitro gastrointestinal model

Cyrille Krul, Anja Luiten-Schuite, Aschwin Tenfelde, Ben van Ommen, Hans Verhagen, Robert Havenaar

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2001

Language:

english

File:

PDF, 343 KB

english, 2001

38

Improving the analysis of designed studies by combining statistical modelling with study design information

Uwe Thissen, Suzan Wopereis, Sjoerd AA van den Berg, Ivana Bobeldijk, Robert Kleemann, Teake Kooistra, Ko Willems van Dijk, Ben van Ommen, Age K Smilde

Journal:

BMC Bioinformatics

Year:

2009

Language:

english

File:

PDF, 319 KB

english, 2009

39

Filling gaps in PPAR-alpha signaling through comparative nutrigenomics analysis

Duccio Cavalieri, Enrica Calura, Chiara Romualdi, Emmanuela Marchi, Marijana Radonjic, Ben Van Ommen, Michael Müller

Journal:

Year:

2009

Language:

english

File:

PDF, 1.87 MB

english, 2009

40

Diagnostic markers based on a computational model of lipoprotein metabolism

Daniël B van Schalkwijk, Ben van Ommen, Andreas P Freidig, Jan van der Greef, Albert A de Graaf

Journal:

Journal of Clinical Bioinformatics

Year:

2011

Language:

english

File:

PDF, 558 KB

english, 2011

41

Studies on the active site of rat glutathione S-transferase isoenzyme 4–4 : Chemical modification by tetrachloro-1,4-benzoquinone and its glutathione conjugate

Ben van OMMEN, Jan H. T. M. PLOEMEN, Hendrik J. RUVEN, Ria M. E. VOS, Jan J. P. BOGAARDS, Willem J. H. van BERKEL, Peter J. van BLADEREN

Journal:

Year:

1989

Language:

english

File:

PDF, 730 KB

english, 1989

42

The glutathione conjugates of tert-butyl hydroquinone as potent redox cycling agents and possible reactive agents underlying the toxicity of butylated hydroxyanisole

Ben van Ommen, Arjen Koster, Hans Verhagen, Peter J. van Bladeren

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 426 KB

english, 1992

43

Inhibition of rat and human glutathione S-transferase isoenzymes by ethacrynic acid and its glutathione conjugate

Jan H.T.M. Ploemen, Ben van Ommen, Peter J. van Bladeren

Journal:

Biochemical Pharmacology

Year:

1990

Language:

english

File:

PDF, 568 KB

english, 1990

44

Irreversible inhibition of human glutathione S-transferase isoenzymes by tetrachloro-1,4-benzoquinone and its glutathione conjugate

Jan H.T.M. Ploemen, Ben Van Ommen, Peter J. Van Bladeren

Journal:

Biochemical Pharmacology

Year:

1991

Language:

english

File:

PDF, 488 KB

english, 1991

45

Interindividual differences in the in vitro conjugation of methylene chloride with glutathione by cytosolic glutathione S-transferase in 22 human liver samples

Jan J.P. Bogaards, Ben van Ommen, Peter J. Van Bladeren

Journal:

Biochemical Pharmacology

Year:

1993

Language:

english

File:

PDF, 404 KB

english, 1993

46

Isoenzyme selective irreversible inhibition of rat and human glutathione S-transferases by ethacrynic acid and two brominated derivatives

Jan H.T.M. Ploemen, Jan J.P. Bogaards, Gerrit A. Veldink, Ben van Ommen, Dilian H.M. Jansen, Peter J. van Bladeren

Journal:

Biochemical Pharmacology

Year:

1993

Language:

english

File:

PDF, 830 KB

english, 1993

47

Stereoselectivity of human liver and intestinal cytosolic fractions as well as purified human glutathione S-transferase isoenzymes towards 2-bromoisovalerylurea enantiomers

Titia M.T. Mulders, Ben Van Ommen, Peter J. van Bladeren, Douwe D. Breimer, Gerard J. Mulder

Journal:

Biochemical Pharmacology

Year:

1993

Language:

english

File:

PDF, 475 KB

english, 1993

48

Polymorphism in the glutathione conjugation activity of human erythrocytes towards ethylene dibromide and 1,2-epoxy-3-(p-nitrophenoxy)-propane

Jan H.T.M. Ploemen, Lars W. Wormhoudt, Ben van Ommen, Jan N.M. Commandeur, Nico P.E. Vermeulen, Peter J. van Bladeren

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

1995

Language:

english

File:

PDF, 910 KB

english, 1995

49

Systematic construction of a conceptual minimal model of plasma cholesterol levels based on knockout mouse phenotypes

Niek C.A. van de Pas, Ans E.M.F. Soffers, Andreas P. Freidig, Ben van Ommen, Ruud A. Woutersen, Ivonne M.C.M. Rietjens, Albert A. de Graaf

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2010

Language:

english

File:

PDF, 450 KB

english, 2010

50

A physiologically-based kinetic model for the prediction of plasma cholesterol concentrations in the mouse

Niek C.A. van de Pas, Ruud A. Woutersen, Ben van Ommen, Ivonne M.C.M. Rietjens, Albert A. de Graaf

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2011

Language:

english

File:

PDF, 818 KB

english, 2011

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